The Influence of Physical Training in Normobaric Hypoxia on Prooxidant-Antioxidant Imbalance, Inflammatory Marker Levels, Intestinal Damage Degree, and Mitochondrial Energy Release Rate in Young Non-trained Males
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
* Cognitive assessment of the influence of a 4-week proprietary training program under normobaric hypoxia conditions on the levels of inflammatory markers, disturbances in prooxidant-antioxidant balance, degree of intestinal damage, and mitochondrial energy production rate in young sedentary males. * Applied objective: Development of practical training guidelines utilizing training in normobaric hypoxia conditions to enhance mechanisms related to oxygen transport, adaptive changes within the immune system, body's antioxidant capacity, gut permeability, substrate utilization efficiency, and mitochondrial function for coaches and athletes.
Eligibility
Participation Requirements
Sex: Male
Minimum Age: 19
Maximum Age: 29
Healthy Volunteers: t
View:
• no known metabolic diseases, no contraindications to physical exercise and no history of high altitude sickness stated in interview. A medical examination (including ECG, blood and urine tests) is required.
Locations
Other Locations
Poland
University School of Physical Education in Cracow
RECRUITING
Krakow
Contact Information
Primary
Anna Radoń, MSc
anna.radon@awf.krakow.pl
+45126831142
Backup
Anna Kałuża, MSc
anna.kaluza@doctoral.awf.krakow.pl
Time Frame
Start Date:2023-02-01
Estimated Completion Date:2026-12
Participants
Target number of participants:50
Treatments
No_intervention: Control group
The control group will not undergo the training program.
Experimental: LHTL (live high - train low)
Training performed under normoxic conditions (223m), stay and sleep in normobaric hypoxic conditions (3000m) and thermoneutral conditions (21°C) and constant humidity (40%).
Experimental: LLTH (live low - train high)
Training performed under normobaric hypoxia conditions (3000m), stay and sleep in normoxic conditions (223m) and thermoneutral conditions (21°C) and constant humidity (40%).~will stay and sleep in normoxic (223m), and train in normobaric hypoxia (3000m)
Experimental: LLTL (live low - train low)
Training performed and stay and sleep in normoxic conditions (223m) and thermoneutral conditions (21°C) and constant humidity (40%).